Effect of ABCA1-V771M polymorphism on plasma lipid levels and its relationship with coronary atherosclerotic heart disease

作     者：Wang D. Li H. Zhang T. Cui H. Shu J. Yang H. Cui C. Muhlestein J.B. 

作者机构：Department of Cardiology First Affiliated Hospital Medical School of Xi'an Jiaotong University Xi'an 710061 China Department of Cardiology Shaanxi Provincial People's Hospital Xi'an 710068 China Cardiology Center of LDS Hospital Salt Lake City UT United States 

出 版 物：《Journal of Pharmaceutical Analysis》 (药物分析学报（英文版）)

年 卷 期：2008年第20卷第2期

页      面：82-87页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：Desert Foundation Salt Lake City USA 

主　　题：ATP-binding cassette transportera A1 (ABCA1) Chinese population Coronary heart disease High density lipoprotein cholesterol Single nucleotide polymorphisms 

摘      要：Objective To explore the risk association of ABCA1-V771M polymorphism with coronary heart disease(CHD)in Han nationality in Northwest of *** With case-control study,ABCA1-V771M polymorphism was detected in 204 unrelated Han nationality people in Northwest of China,and all the subjects by coronary angiography were grouped into 106 cases and 98 *** genotypes and alleles frequency distribution of ABCA1-V771M polymorphisms were analyzed by PCR-RFLP analysis,and the clinical statistics of seru...