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Efficacy and cost analysis of transrectal ultrasound-guided prostate biopsy under monitored anesthesia

Efficacy and cost analysis of transrectal ultrasound-guided prostate biopsy under monitored anesthesia

作     者:Sung Gu Kang Bum Sik Tae Sam Hong Min Young Hwii Ko Seok Ho Kang Jeong Gu Lee Je Jong Kim Jun Cheon 

作者机构:Department of Urology Korea University School of Medicine Korea University Robotic Urologic Surgery Center Korea University Hospital Seoul 136-705 Korea Department of Anesthesiology and Pain Medicine Korea University School of Medicine Korea University Robotic Urologic Surgery Center Korea University Hospital Seou 136-705 Korea 

出 版 物:《Asian Journal of Andrology》 (亚洲男性学杂志(英文版))

年 卷 期:2011年第13卷第5期

页      面:724-727页

核心收录:

学科分类:0831[工学-生物医学工程(可授工学、理学、医学学位)] 0710[理学-生物学] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 07[理学] 08[工学] 071002[理学-动物学] 10[医学] 

主  题:biopsy pain prostate sedation 

摘      要:Sedation may result in reduction in pain during transrectal ultrasound (TRUS)-guided prostate biopsies. We aimed to evaluate the efficacy and safety of a combination of propofol and remifentanil infusion during TRUS-guided prostate biopsy and the related increases in health care costs. From January to September 2010, 100 men undergoing a transrectal prostate biopsy were randomized into two groups. In Group 1, 50 patients received a combined infusion of propofol and remifentanil; in Group 2, 50 patients received lidocaine jelly. After TRUS-guided biopsies were performed, pain and patient satisfaction were evaluated by a lO-point visual analog scale (VAS), and a cost-related patient satisfaction questionnaire was completed by all patients. Patients were also asked whether they would be willing to undergo repeat biopsy by the same method. Patients in Group I showed a significantly lower VAS score than those in Group 2 (mean VAS score: 0.9± 1.1 versus 6.3±2.5; P〈0.001). In addition, the patient satisfaction scale was significantly higher in Group 1 (P=0.002). Although the overall cost was significantly higher in Group 1 (P=0.006), patient satisfaction scales considering cost were also higher in this group (P=0.009). A combination of propofol and remifentanil is a safe and effective way to decrease patient pain and increase patient satisfaction during TRUS-guided prostate biopsy. Although the costs were higher in the group that received sedation, as expected, the patients exhibited heightened satisfaction and willingness to repeat biopsies by the same method.

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