Inflammation-based factors and prognosis in patients with colorectal cancer
Inflammation-based factors and prognosis in patients with colorectal cancer作者机构：Department of Surgical Oncology Osaka City University Graduate School of MedicineOsaka 545-8585 Japan
出 版 物：《World Journal of Gastrointestinal Oncology》 (世界胃肠肿瘤学杂志（英文版）（电子版）)
年 卷 期：2015年第7卷第8期
页 面：111-117页
核心收录：
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
主 题：Colorectal cancer Platelet-to-lymphocyteratio Prognosis Glasgow Prognostic Score C-reactiveprotein Neutrophil-to-lymphocyte ratio Inflammationbasedfactor Nutritional Prognostic Index
摘 要：Several parameters for predicting survival in patients with colorectal cancer have been identified, including the performance status, age, gender and tumor-nodemetastasis(TNM) stage. Although the TNM stage is important and useful for predicting the prognosis and determining the appropriate treatment, it is well known that the survival time varies widely, even in patients with the same stage of disease. Therefore, the identification of new parameters capable of more precisely predicting patient survival is needed to help select the optimal treatment, especially in patients in the advanced stage of disease. Although the TNM stage reflects the tumor characteristics, cancer progression and survival are not determined solely based on the local characteristics of the tumor, but also the host systemic immune/inflammatory response. Therefore, using a combination of parameters that reflect both tumor characteristics and the host systemic inflammatory status is thought to be important for accurately predicting patient survival.
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