坏疽性脓皮症是系统性红斑狼疮的前期表现
Pyoderma gangrenosum preceding the diagnosis of systemic Lupus erythematosus作者机构：310 E. Broadway Louisville KY 40202 United States
出 版 物：《世界核心医学期刊文摘（皮肤病学分册）》 (Digest of the World Core Medical JOurnals:Dermatology)
年 卷 期：2005年第1卷第5期
页 面：30-30页
学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
主 题：系统性红斑狼疮 脓皮症 坏疽性脓皮病 抗磷脂抗体 血管炎 炎性肠病 皮肤溃疡 嗜中性 下肢溃疡 多发性关节炎
摘 要：Patients with systemic lupus erythematosus (SLE)often develop leg ulceration, particularly those with antiphospholipid antibodies or with vasculitis. Pyoderma gangrenosum (PG)is an idiopathic ulcerative neutrophilic dermatosis that is com monly associated with inflammatory bowel disease or seronegative polyarthritis. Although PG-like lesions have been commonly described in patients with the anti phospholipid antibody syndrome, the occurrence of PG as a preceding manifestatio n of SLE has only rarely been reported. We present a patient who developed PG ro ughly 8 years prior to developing SLE.
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