Effects of closing and reopening live poultry markets on the epidemic of human infection with avian influenza A virus

作     者：Jian Lu Wendong Liu Rui Xia Qigang Dai Changjun Bao Fenyang Tang Yefei Zhu Qiao Wang 

作者机构：School of Information Science and EngineeringSoutheast University Department of Acute Infectious Disease Control and PreventionJiangsu Provincial Center for Disease Control and Prevention Center of Laboratory MedicineThe Second Affiliated Hospital of Nanjing Medical University 

出 版 物：《The Journal of Biomedical Research》 (生物医学研究杂志（英文版）)

年 卷 期：2016年第30卷第2期

页      面：112-119页

核心收录：

学科分类：0710[理学-生物学] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 100401[医学-流行病与卫生统计学] 10[医学] 

主　　题：live poultry market avian influenza A(H7N9) 

摘      要：Live poultry markets（LPMs） are crucial places for human infection of influenza A（H7N9 virus）.In Yangtze River Delta,LPMs were closed after the outbreak of human infection with avian influenza A（H7N9） virus,and then reopened when no case was *** purpose was to quantify the effect of LPMs＇ operations in this region on the transmission of influenza A（H7N9） *** obtained information about dates of symptom onset and locations for all human influenza A（H7N9） cases reported from Shanghai,Jiangsu and Zhejiang provinces by May 31,2014,and acquired dates of closures and reopening of LPMs from official media.A two-phase Bayesian model was fitted by Markov Chain Monte Carlo methods to process the spatial and temporal influence of human cases.A total of 235 cases of influenza A（H7N9） were confirmed in Shanghai,Jiangsu and Zhejiang by May 31,*** these data,our analysis showed that,after LPM closures,the influenza A（H7N9） outbreak disappeared within two weeks in Shanghai,one week in Jiangsu,and one week in Zhejiang,*** authorities reopened LPMs when there was no outbreak of influenza A（H7N9）,which did not lead to reemergence of human influenza A（H7N9）.LPM closures were effective in controlling the H7N9 *** of LPM in summer did not increase the risk of human infection with *** findings showed that LPMs should be closed immediately in areas where the H7N9 virus is confirmed in *** there is no outbreak of H7N9 virus,LPMs can be reopened to satisfy the Chinese traditional culture of buying live *** the long term,local authorities should take a cautious attitude in permanent LPM closure.