Interferon-α induced severe thrombocytopenia:A case report and review of the literature

作     者：Li Li,Da-Kang Han,Jun Lu,Tumor Biotherapy Ward of Beijing Youan Hospital,Capital Medical University,Beijing 100069,China 

作者机构：Tumor Biotherapy Ward of Beijing Youan Hospital Capital Medical University Beijing 100069 China. 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2010年第16卷第11期

页      面：1414-1417页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：Supported by National High Technology Research and Development Program of China No.2007AA02Z151 to Lu J 

主　　题：Interferon-α Severe thrombocytopenia Chronic hepatitis C 

摘      要：We report a case of severe thrombocytopenia following pegylated interferon-α 2a(Peg-IFN-α 2a)treatment of hepatitis C virus infection and summarize the clinical characteristics of 16 cases of IFN-α induced severe thrombocytopenia and its immune-mediated *** of IFN-α and early administration of immunosuppressants are the effective therapy for IFN-αinduced severe thrombocytopenia.