Procedural learning changes in patients with Wilson's disease

作     者：Yumei Jiang Xiang Shen Xiaoping Wang Wenjie Li 

作者机构：Department of Neurology First People's Hospital of Shanghai Jiao Tong University Shanghai 200080 China 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2011年第6卷第18期

页      面：1410-1414页

核心收录：

学科分类：0711[理学-系统科学] 07[理学] 081104[工学-模式识别与智能系统] 08[工学] 081402[工学-结构工程] 081304[工学-建筑技术科学] 0813[工学-建筑学] 0814[工学-土木工程] 0811[工学-控制科学与工程] 071102[理学-系统分析与集成] 081103[工学-系统工程] 

基　　金：the National Natural Science Foundation of China  No. 81071065/H0914 

主　　题：Wilson's disease basal ganglia procedural learning Wechsler Memory Scale sedal reaction time task cognitive neuroscience neural regeneration 

摘      要：In the present study, we compared explicit memory performance, using the Wechsler Memory Scale and implicit memory performance, using the Nissen software version of the serial reaction time task, in patients with Wilson＇s disease to normal controls. The Wilson＇s disease patients exhibited deficits in explicit memory tasks, such as figure recall and understanding memory. Moreover, the Wilson＇s disease patients exhibited deficits in implicit memory tasks, including significantly prolonged response times. These findings indicate that Wilson＇s disease patients have explicit and implicit partial memory impairments.