Improving Long-Term Functional Outcomes of Ischemic Stroke in the Reperfusion Era

作     者：Chuanjie Wu Xuehong Chu Zhanwei Zhu Di Wu Xunming Ji Chuanjie Wu;Xuehong Chu;Zhanwei Zhu;Di Wu;Xunming Ji

作者机构：Department of NeurologyXuanwu Hospital Capital Medical UniversityBeijing 100053China China-America Institute of NeuroscienceXuanwu Hospital Capital Medical UniversityBeijing 100053China 

出 版 物：《Engineering》 (工程（英文）)

年 卷 期：2024年第40卷第9期

页      面：15-18页

核心收录：

学科分类：1002[医学-临床医学] 100204[医学-神经病学] 10[医学] 

基　　金：supported by the National Natural Science Foundation of China(82027802 82371470 and 82071468) 

主　　题：acute treatment spite 

摘      要：*** Stroke remains the second leading cause of death and the third leading cause of death and disability combined worldwide,as indicated by disability-adjusted life-years(DALYs)lost[1].The highest burden of stroke disability is observed in developing countries of Asia and the stroke belt of the United States[2].Despite remarkable progress and advancements in evidence-based acute care therapies,such as intravenous thrombolysis and endovascular therapy,the burden of stroke remains significantly high[3].In 2023,a significant advancement in the treatment of ischemic stroke due to proximal intracranial arterial occlusion was marked by compelling evidence from several clinical trials that supported endovascular therapy,particularly for patients with a large ischemic core[4].Thus,endovascular therapy has entered a new era since the first clinical trial favoring endovascular ***,more patients receiving endovascular therapy does not equal a better *** with stroke experience long-term dysfunction,and the percentage is much higher in patients with large ischemic ***,numerous tasks must be performed to optimize acute stroke treatment strategies and improve rehabilitative care.