Comparison of anti-vascular endothelial growth factors, laser treatments and a combination of the both for treatment of central retinal vein occlusion
Comparison of anti-vascular endothelial growth factors,laser treatments and a combination of the both for treatment of central retinal vein occlusion作者机构：Tzameret Medical Track Hebrew University Jerusalem 91120 Israel Research Wing Ziv Medical Center Safed Israel and Tel-Hal Academic College Kiryat Shmona 12208 Israel Department of Ophthalmology Rambam Medical Center Haifa 3525408 Israel The B. Rappaport Faculty of Medicine Israel Institute of Technology Haifa 3525427 Israel Departrnent of Ophthalmology Ziv Medical Center Safed 13100 Israel Bar Ilan University Faculty of Medicine Safed 13101 Israel
出 版 物：《International Journal of Ophthalmology(English edition)》 (国际眼科杂志（英文版）)
年 卷 期：2016年第9卷第3期
页 面：431-433页
核心收录：
学科分类：1002[医学-临床医学] 100212[医学-眼科学] 10[医学]
主 题：bevacizumab grid laser photocoagulation macular edema optical coherence tomography retinal veinocclusion
摘 要：AIM：To compare changes in visual acuity and macular edema in patients with central retinal vein occlusion（CRVO）treated with intravitreal injections of bevacizumab,macular grid photocoagulation combined with pan retinal photocoagulation（PRP）,or both（bevacizumab＋grid＋PRP）.· METHODS：Our study is a retrospective cohort clinical study that examined patients that suffered from ischemic CRVO with macular *** inclusion criteria were ischemic CRVO with macula edema and the availability of complete medical records for at least 12 mo after *** were patients with diabetes or any other retinal *** reviewed the medical records of patients treated in one ophthalmology departmentcomparing changes in visual acuity and macular edema in patients treated with intravitreal injections of bevacizumab vs those that were treated with macular grid photocoagulation and PRP or *** main outcome measures were the differences in best corrected visual acuity（BCVA） and in macular thickness,as assessed by optical coherence tomography,between the enrollment and the final follow up visits.· RESULTS：Sixty-five patients met inclusion *** were no statistically significant differences among the three groups in the mean changes in macular thickness as measured by ocular coherence tomography（131.5±41.2,108.6±29.2,and 121.1±121.1,P=0.110）,or in visual acuity（0.128±0.077,0.088±0.057,and 0.095±0.065）,for intravitreal injections,macular grid photocoagulation＋PRP and a combination of the treatments,respectively,P =*** proportions of patients with macular edema after treatment were：26.1%,28.6%,and 14.3%,respectively,P=0.499.· CONCLUSION：Similar benefit was observed for intravitreal injections,laser photocoagulation,or a combined regimen in the treatment of CRVO.A nonstatistically significant trend for reduction in macular edema was observed following combined treatment.
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