Early markers of reperfusion injury after liver transplantation: association with primary dysfunction

作     者：Helge Bruns Jan Heil Daniel Schultze Mohammed Al Saeedi Peter Schemmer 

作者机构：Department of General and Transplant Surgery University Hospital Heidelberg 

出 版 物：《Hepatobiliary & Pancreatic Diseases International》 (国际肝胆胰疾病杂志（英文版）)

年 卷 期：2015年第14卷第3期

页      面：246-252页

核心收录：

学科分类：1002[医学-临床医学] 10[医学] 

基　　金：supported by an unrestricted grant from Novartis Pharma Gmb H Nürnberg Germany 

主　　题：primary dysfunction liver transplantation predictive markers reperfusion injury microarray 

摘      要：BACKGROUND： In patients with end-stage fiver disease, fiver transplantation is the only available curative treatment. Al- though the outcome and quality of life in the patients have improved over the past decades, primary dys- or nonfimction （PDF/PNF） can occur. Early detection of PDF and PNF is crucial and could lead to individual therapies. This study was designed to identify early markers of reperfusion injury and PDF in liver biopsies taken during the first hour after reperfusion.