Collision tumor of the rectum: A case report of metastatic gastric adenocarcinoma plus primary rectal adenocarcinoma
Collision tumor of the rectum: A case report of metastatic gastric adenocarcinoma plus primary rectal adenocarcinoma作者机构：Department of Surgery Dong-A University College of Medicine Busan 602-715 South Korea Department of Pathology Dong-A University College of Medicine Busan 602-715 South Korea Department of Rehabilitation Medicine Dong-A University College of Medicine Busan 602-715 South Korea Department of Pathology Dong-A University College of Medicine Busan 602-715 South Korea Medical Research Center for Cancer Molecular Therapy Dong-A University College of Medicine Busan 602-715 South Korea
出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)
年 卷 期：2006年第12卷第34期
页 面：5569-5572页
核心收录：
学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学]
基 金：Supported by the Korea Science and Engineering Foundation through the MRCCMT at Dong-A University
主 题：Collision tumor Rectum Clonality
摘 要：Collision tumors are thought to arise from the accidental meeting and interpenetration of two independent tumors. We report here a highly unusual case of a 61-year old man who had a unique tumor that was composed of a metastatic adenocarcinoma from the stomach to the rectum, which harbored a collision tumor of primary rectal adenocarcinoma. The clonalities of the two histologically distinct lesions of the rectal mass were confirmed by immunohistochemical and molecular analysis. Although histologic examination is the cornerstone in pathology, immunohistochemical and molecular analysis can provide evidence regarding whether tumors originate from the same clone or different clones. To the best of our knowledge, this is the fi rst reported case of such an occurrence.
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