Molecular modeling of oscillating GHz electric field influence on the kinesin affinity to microtubule

作     者：H.R.Saeidi S.S.Setayandeh A.Lohrasebi 

作者机构：Department of Physics University of Isfahan Computational Nano-Bioelectromagnetics Research Group School of Nano-Science Institute for Research in Fundamental Sciences (IPM) 

出 版 物：《Chinese Physics B》 (中国物理B（英文版）)

年 卷 期：2015年第24卷第8期

页      面：239-242页

核心收录：

学科分类：0710[理学-生物学] 07[理学] 071009[理学-细胞生物学] 09[农学] 0901[农学-作物学] 090102[农学-作物遗传育种] 

主　　题：kinesin affinity oscillating electric field molecular dynamic αβ-tubulin dimer 

摘      要：Kinesin is a microtubule-associated motor protein which can respond to the external electric field due to its *** a molecular dynamics simulation method, the effect of such a field on the affinity of kinesin to the α β-tubulin is investigated in this study. To consider kinesin affinity, the system is exposed to an electric field of 0.03 V/nm with frequency values of 1, 2,..., 9, and 10 GHz. It is found that the applied electric field can change kinesin affinity to the *** changes could perturb the normal operation of kinesin, such as the processive motility of kinesin on the microtubule.