Chiral Separation of Ibuprofen and Terbutaline by Nonaqueous Capillary Electrophoresis with Conductance Detection

作     者：DENG Guang-hui WEI Shou-lian MO Jin-yuan 

作者机构：Department of ChemistryGuangxi University for NationalitiesNanning 530006P.R.China Department of ChemistryZhongshan UniversityGuangzhou 510275P.R.China 

出 版 物：《Chemical Research in Chinese Universities》 (高等学校化学研究(英文版))

年 卷 期：2002年第18卷第1期

页      面：16-19页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070302[理学-分析化学] 0703[理学-化学] 

基　　金：Supported by the Natural Science Foundation of Guangxi Province(No.9912 0 0 1) 

主　　题：Nonaqueous medium Capillary electrophoresis with conductance detection Sulfonyl β -CD Resolution N,N -Dimethylformamide 

摘      要：In the nonaqueous N,N -dimethylformamide medium, the chiral drugs ibuprofen and terbutaline were successfully separated with sulfonyl- β -cyclodextrin(s- β -CD) as the chiral selector by capillary electrophoresis with conductance detection. The comparison of the effects of three CDS( β -CD, diethylic- β -CD, sulfonyl- β -CD) on the chiral separation was made and the resolution mechanism was proposed.