Further evaluation of coronary artery with 16-multidetector CT coronary angiography

作     者：刘昌伟 黄向明 张连贵 

作者机构：Department of Radiology Department of CardiologyShenzhen Baoan District Guanlan People's Hospital 

出 版 物：《South China Journal of Cardiology》 (岭南心血管病杂志（英文版）)

年 卷 期：2011年第12卷第2期

页      面：107-111,130页

学科分类：0831[工学-生物医学工程（可授工学、理学、医学学位）] 100207[医学-影像医学与核医学] 1006[医学-中西医结合] 1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 08[工学] 1010[医学-医学技术（可授医学、理学学位）] 100106[医学-放射医学] 100602[医学-中西医结合临床] 10[医学] 

主　　题：coronary artery 16-muhidetector CT 64-muhidetector CT angiography heart rate 

摘      要：Background In the past 20 years, non-invasive coronary imaging technology has developed rapidly, the 16- multidetector CT has accumulated abundant experiences for the clinical application of 64-multidetector CT. We evaluated the result of 706 patients being studied by the 16-multidetetor coronary angiography, providing the evidences for early diagnosis and reliable evaluation. Methods Seven hundred and six patients underwent 16- multideteeor coronary angiography, among which 537 received regular doses of [3 receptor blockers, maintaining their heart rates amidst 65 ± 10beats/min （bpm）. The retrospective ECG gating was used to generate images （slice thickness 1125 mm, pitch 0.257：1）. The contrast injection was 115-2 mm/kg bolus of nonionie contrast material （300 or 370 mg of iodine per milliliter） at flow rate 3-4 mL/s. After injection of contrast material, the patients were instructed to breath-hold for 20 seconds to ensure clear visualization and reliable evaluation of the main coronary artery and its branches （left main coronary, left anterior descending, left circumflex, and right coronary）. The postprocessing was done by volume rendering （VR）, Maximum intensity projection （MIP）, and Virtual Endoscopy （VE）. Result Two thousand five hundred and fifty six coronary arteries were included in the studies. Sensitivity, specificity, accuracy, and positive and negative predictive values for the whole study group were 96 %, 88 %, 89 %, 91%, 93 %, respectively. Significant stenosis （diameter stenosis 1〉50 %） were detected in 936 of 2556 arteries, including calcified stenosis 773/936 （82.59 %）, noncalcified plaque stenosis 163/936 （17.41%）, single branches significant stenosis 612/936 （65.38 %）, two-branch significant stenosis 237/936 （22.32 %）, more than three branches significant stenosis 113/936 （12.07 %）. Conclusions The technically improved 16-muhideetor CT, with better heart rate control and scanning techniques, permits satisfactory visualization of the main coronary