Analysis of TORCH results of retinal exudative changes in neonates

作     者：Cen Chao He Liying Tao Xueying Liu Ya 岑超;何俐莹;陶雪莹;刘娅

作者机构：Department of OphthalmologyChongqing Health Center for Women and ChildrenWomen and Children's Hospital of Chongqing Medical UniversityChongqing 401147China 

出 版 物：《国际眼科杂志》 (International Eye Science)

年 卷 期：2024年第24卷第9期

页      面：1367-1372页

学科分类：1002[医学-临床医学] 100211[医学-妇产科学] 10[医学] 

基　　金：重庆市社会事业与民生保障科技创新专项重点研发项目(No.cstc2017shms-zdyfX0049) 

主　　题：neonates TORCH infection retinal exudation 

摘      要：AIM:To explore the relationship between retinal exudative changes in neonates and perinatal toxoplasmosis,others,rubella,cytomegalovirus,and herpes simplex virus(TORCH)infections,as well as the characteristics of TORCH infection in neonates with retinal exudative ***:Retrospective study.A total of 612 neonates with retinal exudative changes detected during ophthalmic screening in our hospital from May 2019 to March 2023 were *** tests were performed on these neonates,and the results were subjected to statistical analysis to determine the infection *** neonates with retinal exudative changes were grouped by sex and age,the characteristics of TORCH infection were analyzed,and the positive rates were ***:Among the 612 neonates with retinal exudative changes,the highest positive rate was observed for cytomegalovirus(CMV-IgG)(96.7%),followed by rubella virus(RV-IgG)(73.9%).Mixed infections with two or three viruses were also observed,with the highest positive rate for mixed infection of RV-IgG and CMV-IgG reaching 71.2%.There was no statistically significant difference in TORCH infection among neonates of different sex(P0.05).However,there were statistically significant differences in RV-IgG and CMV-IgM infections with retinal exudative changes among neonates of different age groups(P0.05).CONCLUSION:Perinatal TORCH infection may be an important factor causing retinal exudative changes in *** differences in various infections are not related to sex but are related to different age groups.