Studies on the Antioxidant Potential of Extracts from Unripe Fruit of Carica papaya
Studies on the Antioxidant Potential of Extracts from Unripe Fruit of Carica papaya作者机构：Biochemistry Department University of Ado-Ekiti Ekiti State 5363 Nigeria Departmento de Quimica Bioquimica Toxicologia （CCNE） Universidade Federal de Santa Maria Santa Maria 97105-900 Brazil
出 版 物：《Journal of Life Sciences》 (生命科学（英文版）)
年 卷 期：2012年第6卷第1期
页 面：41-47页
学科分类：0832[工学-食品科学与工程（可授工学、农学学位）] 08[工学] 09[农学] 083201[工学-食品科学] 0902[农学-园艺学] 090201[农学-果树学]
主 题：Carica papaya thiobarbituric reactive species antioxidant activity lipid peroxidation.
摘 要：The antioxidant activities of the ethyl acetate fraction and aqueous extract of unripe fruit of Carica papaya were compared and investigated in vitro using thiobarbituric reactive species （TBARS） assay, total phenol content, evaluation of reactive oxygen species （ROS） in liver mitochondria, Fe2＋ chelating and 2,2-diphenyl-lpicrylhydrazyl （DPPH） scavenging activities. Both extracts had high antioxidant properties and could inhibit FeE＋ and sodium nitroprusside lipid peroxidation in the liver. Total phenol content of ethyl acetate fraction and aqueous extract were 4.50 ±2.26 and 1.21±3.12 mg/g, respectively. Both extracts had a maximal effect at the lowest concentrations tested （15 μg/mL for ethyl acetate and 150 μg/mL for the aqueous）. Ethyl acetate fraction showed that the highest values of antioxidant activity is probably associated with its high phenolic content, Fe2＋ chelating and DPPH scavenging activities. It is therefore concluded that ethyl acetate fraction and to a less extent the aqueous fractions are potent inhibitor of lipid peroxidation.
维普期刊数据库