Location of Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus in Tissues of Natural Cases

作     者：刘永宏 赵丽 韩春华 王凤龙 刘月焕 林健 杨汉春 郭鑫 李栋梁 韦海涛 祝俊杰 赵景义 赵振华 马明 杨龙峰 王金玲 LIU Yong-hong;ZHAO Li;HAN Chun-hua;WANG Feng-long;LIU Yue-huan;LIN Jian;YANG Han-chun;GUO Xin;LI Dong-liang;WEI Hai-tao;ZHU Jun-jie;ZHAO Jing-yi;ZHAO Zhen-hua;MA Ming;YANG Long-feng;WANG Jin-ling

作者机构：内蒙古农业大学动物科学与医学学院内蒙古呼和浩特010018 北京市农林科学院畜牧兽医研究所北京100097 中国农业大学动物医学院北京100094 北京市延庆县动物卫生监督管理局北京102100 北京市畜牧兽医总站北京100029 

出 版 物：《Agricultural Science & Technology》 (农业科学与技术（英文版）)

年 卷 期：2009年第10卷第2期

页      面：20-25页

学科分类：0710[理学-生物学] 090601[农学-基础兽医学] 07[理学] 09[农学] 0906[农学-兽医学] 071002[理学-动物学] 

基　　金：北京市农林科学院青年基金项目(2007020122) 北京市科委猪高致病性蓝耳病防控技术子课题 

主　　题：Highly Pathogenic Porcine Reproductive and Respiratory Syndrome Virus Natural case Immunohistochemistry Antigen location 

摘      要：[ Objective] The aim of this study was to provide a theoretical basis for the prevention and treatment of highly pathogenic porcine reproductive and respiratory syndrome （HP-PRRS）. [Method] Antigen location and histopathological observation in natural cases infected by highly pathogenic porcine reproductive and respiratory syndrome virus （HP-PRRSV） were analyzed by immunohistochemistry and H. E. staining. [Result] The virus antigen mainly existed in epithelial calls, and also a few in mecrophages, lymphocytes and brain nerve cells. [ Conclusion] The cell and tissue tropism of HP-PRRSV strain in natural cases is different from that of previous strains.