Evaluation of corneal parameter changes under different accommodative stimuli with Scheimpflug imaging-based tomography

作     者：Farid J Bedrán-García David P Piñero Farid J Bedrán-García;David P Piñero

作者机构：Department of OpticsPharmacology and AnatomyUniversity of AlicanteAlicante 03690Spain 

出 版 物：《国际眼科杂志》 (International Eye Science)

年 卷 期：2024年第24卷第9期

页      面：1357-1366页

学科分类：1010[医学-医学技术（可授医学、理学学位）] 10[医学] 

主　　题：corneal biomechanics keratometry corneal thickness pachymetry corneal aberrations Pentacam accommodation 

摘      要：AIM:To evaluate the reliability of measurements of corneal changes with accommodation in healthy eyes using a Scheimpflug imaging-based system and how these measurements distribute in the normal ***:Prospective,non-randomized,comparative study including 27 healthy subjects(54 eyes),including emmetropia(13 eyes),myopia(17 eyes),hyperopia(4 eyes)and astigmatism(20 eyes)*** all cases,a complete eye examination was performed,including the analysis of corneal changes with different accommodative stimuli(+2.00,0.00 and-3.00 D)using the Pentacam AXL *** investigation was structured in 2 phases:repeatability analysis and characterization of accommodation-related corneal changes in healthy ***:In the repeatability analysis,the index of height asymmetry(IHA)showed the greatest variability with the three accommodative stimuli,being the results for the rest of parameters *** group of emmetropes showed significant differences with accommodative changes in the position of maximum keratometry(Kmax;P0.05),whereas in the astigmatism group,significant changes were not only observed in the position of Kmax,but also in minimum corneal thickness(MCT),corneal spherical aberration,and total and low order aberration root mean square(all P0.05).Likewise,a significant difference was found in the displacement of the X position of Kmax with+2.00 D and-3.00 D in the myopia group(P=0.033)as well as in changes with+2.00 D and-3.00 D in the magnitude of the position vector of Kmax in the emmetropia group(P0.05).No significant changes were found between accommodative stimuli in the displacement of coordinates of MCT(P≥0.109).CONCLUSION:The position of Kmax and MCT in healthy corneas can change significantly when presenting different accommodative stimuli using the accommodation mode of the Pentacam system,with different trends in these accommodation-related corneal changes between refractive ***,the consistency of the measurement