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Obstructive sleep apnea-hypopnea syndrome immunological relationship

作     者:Mahmoud Ali Alaa Ramadan Salim Surani 

作者机构:Department of MedicineAl-Azhar UniversityDamietta 11651Egypt Department of MedicineSouth Valley UniversityQena 83523Egypt Department of Medicine and PharmacologyTexas A&M UniversityCollege StationTX 77843United States Department of AnesthesiologyMayo ClinicRochesterMN 55905United States 

出 版 物:《World Journal of Clinical Cases》 (世界临床病例杂志)

年 卷 期:2024年第12卷第27期

页      面:6011-6014页

学科分类:1002[医学-临床医学] 1001[医学-基础医学(可授医学、理学学位)] 100102[医学-免疫学] 100201[医学-内科学(含:心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主  题:Obstructive sleep apnea Mendelian randomization Lymphocyte charac-teristics Immunology Obstructive sleep apnea-hypopnea syndrome 

摘      要:Obstructive sleep apnea-hypopnea syndrome(OSAHS)is a complex disorder cha-racterized by symptoms resulting from intermittent hypoxia and hypopnea,with research indicating a crucial role of immune system dysregulation and genetic variations in its pathogenesis.A recent Zhao et al study utilizes Mendelian ran-domization analysis to explore the causal relationship between immune cell characteristics and *** study identifies specific lymphocyte subsets as-sociated with OSAHS,providing valuable insights into the disease s pathophy-siology and potential targets for therapeutic *** findings underscore the significance of genetic and immunological factors in sleep disorders,offering a fresh perspective on OSAHS s *** to existing literature,Zhao et al s study stands out for its focus on genetic markers and specific immune responses associated with OSAHS,expanding upon previous research primarily centered on systemic *** conclusion,the study represents a signi-ficant advancement in the field,shedding light on the causal role of immune cells in OSAHS and paving the way for future research and targeted treatments.

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