A child with pulmonary and liver Langerhans＇-cell histiocytosis

作     者：MA Xiao-li SHEN Kun-ling WANG Bin 

作者机构：Hematology CenterBeijing Children's Hospital Affiliated to Capital Medical UniversityBeijing 100045China 

出 版 物：《Chinese Medical Journal》 (中华医学杂志（英文版）)

年 卷 期：2012年第125卷第9期

页      面：1675-1676页

核心收录：

学科分类：0710[理学-生物学] 07[理学] 08[工学] 09[农学] 071006[理学-神经生物学] 071007[理学-遗传学] 0901[农学-作物学] 0836[工学-生物工程] 090102[农学-作物遗传育种] 

主　　题：Langerhans '-cell histiocytosis pulmonary liver child 

摘      要：Clinical categories of Langerhans cell histiocytosis （LCH） include single and multi-system disease. Pulmonary LCH is rare, which is an unusual interstitial lung disease with the characteristics of monoclonal proliferation and infiltration of Langerhans＇ cells to organs. We report our experience of a rare LCH case of multiple organs such as pulmonary and liver as the main clinical manifestation. The patient was treated with chemotherapy which included prednisone, vinblastine, methotrexate and 6-mercaptopurine for 52 weeks and follow up all along. The patient has a favorable clinical outcome.