Effects of stellate ganglion block on erythrocyte immunity in patients with acute cerebral infarction

作     者：HE Chun-jing YU Qian FENG Ya-ping LIANG Dai-yi RAN Yan HE Chun-jing;YU Qian;FENG Ya-ping;LIANG Dai-yi;RAN Yan

作者机构：Department of Anesthesiology Guizhou Provincial People's HospitalGuiyang 550002 China Department of Neurology Guizhou Provincial People's HospitalGuiyang 550002 China 

出 版 物：《中华麻醉学杂志》 (Chinese Journal of Anesthesiology)

年 卷 期：2010年第30卷第B2期

页      面：46-49页

核心收录：

学科分类：083002[工学-环境工程] 0830[工学-环境科学与工程（可授工学、理学、农学学位）] 07[理学] 08[工学] 0906[农学-兽医学] 09[农学] 0903[农学-农业资源与环境] 0713[理学-生态学] 

基　　金：the Health Department of Guizhou Province  China(2005138) 

主　　题：红细胞免疫功能 神经节 脑梗塞 超氧化物歧化酶活性 患者 急性 红细胞C3b受体花环率 C3bRR 

摘      要：Objective To investigate the effects of stellate ganglion block (SGB) on erythrocyte immunity in patients with acute cerebral *** Twenty-four patients (13 male, 11 female) who developed acute cerebral infarction for less than 3 days were randomly divided into 2 groups (n=12each): Group A receiving traditional treatment and Group B receiving traditional treatment + *** patients ranged in age from 51 to 64 yr and weighed 52-71 kg. All patients received intravenous 5% glucose 25 ml plus citicoline sodium 1.0 g and sodium ozagrel injectio 250 ml daily for 10 days in addition to dehydration and effective control of complications and intracranial pressure. Group B received SGB on one side alternatively with 1% licocaine 10 mi once a day for 10 days. Fasting venous blood samples were taken in the early mornings of the day before treatment (baseline, T1 ) and the 1st, 5th and 10th day of treatment (T2-4) for determination of the plasma MDA concentration and SOD activity, erythrocyte C3b receptor rosette rate (RBC-C3bRR) and RBC immune complex rosette rate (RBC-ICR) and Ne+-K+-ATPase activity in erythrocyte *** The plasma MDA concentration and RBC-ICR were significantly decreased during treatment es compared with the baselines at T1 in both groups (P0.05 or 0.01), but were significantly lower in Group B than in Group A (P0.05 or 0.01 ).The activities of plasma SOD and Na+ -K+ -ATPase in erythrocyte membrane and RBC-C3bRR were significantly increased during treatment as compared with the baselines at T1 and were significantly higher in Group B than in Group *** SGB combined with traditional treatment can increase the activities of plasma SOD and Na+ -K+ -ATPase in erythrocyte membrane, inhibit production of oxygen free radicals and enhance RBC immune function in patients with acute cerebral infarction.