Relationship between the expression of matrix metalloproteinase-9 and angiogenesis in glioma and its clinical significance

作     者：Yang X. Liu M. Wang M. Liu S. Wang T. Wang H. 

作者机构：Medical Center of Rehabilitation First Affiliated Hospital Medical School of Xi'an Jiaotong University Xi'an 710061 China Department of Neurosurgery First Affiliated Hospital Medical School of Xi'an Jiaotong University Xi'an 710061 China Department of Pathology First Affiliated Hospital Medical School of Xi'an Jiaotong University Xi'an 710061 China 

出 版 物：《Journal of Pharmaceutical Analysis》 (药物分析学报（英文版）)

年 卷 期：2008年第20卷第2期

页      面：113-118页

学科分类：0710[理学-生物学] 1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基　　金：the Scientific and Technological Planning Foundation of Shaanxi Province (2003K10-G80) 

主　　题：Angiogenesis Glioma Invasion Matrix metalloproteinase-9 

摘      要：Objective To explore the role and significance of matrix metalloproteinase-9(MMP-9)in angiogenesis through observing the relationship between the expression of MMP-9 and microvessel density(MVD)in *** The expressions of MMP-9 and CD34 in 10 cases of normal brain tissues and 58 cases of glioma(14 cases of grade Ⅰ,20 cases of grade Ⅱ,15 cases of grade Ⅲ,and 9 cases of grade Ⅳ)were detected by immunohistochemical streptavidin-peroxidase *** positive cells of MMP-9 and the positive microves...