Clinical features and risk factors for invasive fungal sinusitis after allogeneic hematopoietic stem cell transplantation

作     者：付海霞 FU Haixia

作者机构：Peking Univ People's HospPeking Univ Insit HematolNatl Clin Hematol Dis Res CenterBeijing Hematopoiet Stem Cell Transplant Key LabBeijing 100044 

出 版 物：《China Medical Abstracts(Internal Medicine)》 (中国医学文摘（内科学分册（英文版）)

年 卷 期：2024年第41卷第2期

页      面：118-119页

学科分类：1002[医学-临床医学] 1010[医学-医学技术（可授医学、理学学位）] 100213[医学-耳鼻咽喉科学] 100215[医学-康复医学与理疗学] 10[医学] 

主　　题：IFR ratio invasive 

摘      要：Objective To analyze the clinical characteristics and outcomes of patientswith invasive fungal sinusitis(invasive fungal rhinosinusitis,IFR)after allogeneic hematopoietic stem cell transplantation(allo-HSCT)and explored the risk factors for IFR after *** Nineteen patients with IFR after allo-HSCT at Peking University People s Hospital from January 2012 to December 2021 were selected as the study group,and 95 patients without IFR after allo-HSCT during this period were randomly selected as the control group(1:5 ratio).Results Nineteen patients,including 10 males and 9 females,had IFR after *** median age was 36(10-59)*** median IFR onset time was 68(9-880)days after *** wereseven patients with acute myeloid leukemia,five with acute lymphoblastic leukemia,two with myelodysplastic syndrome,two with chronic myeloid leukemia,one with acute mixed-cell leukemia,one with multiple myeloma,and one with T-lymphoblastic lymph node *** were 13 confirmed cases and 6 clinically diagnosed *** responsible fungus was Mucor in two cases,Rhizopus in four,Aspergillus in four,and Candida in three.