Integrated Eco-Health approach significantly reduces helminth infections in endemic Khong islands with emphasis on Schistosoma mekongi

作     者：Somphou Sayasone Youthanavanh Vonghachack Shang Xia Shan Lv Xiao-Nong Zhou Peter Odermatt Somphou Sayasone;Youthanavanh Vonghachack;Shang Xia;Shan Lv;Xiao-Nong Zhou;Peter Odermatt

作者机构：Lao Tropical and Public Health InstituteMinistry of HealthVientiane CapitalLao PDR Faculty of Basic SciencesUniversity of Health SciencesVientiane CapitalLao PDR National Institute of Parasitic Diseases at China CDC(Chinese Center for Tropical Diseases Research)NHC Key Laboratory of Parasite and Vector BiologyWHO Collaborating Centre for Tropical DiseasesShanghai 200025PR China Department of Public Health and EpidemiologySwiss Tropical and Public Health InstituteAllschwilSwitzerland University of BaselBaselSwitzerland 

出 版 物：《Infectious Diseases of Poverty》 (贫困所致传染病（英文）)

年 卷 期：2024年第13卷第4期

页      面：64-78页

核心收录：

学科分类：0202[经济学-应用经济学] 02[经济学] 020205[经济学-产业经济学] 

基　　金：This intervention study was funded by the International Development Research Centre Foreign Affairs,Trade and Development Canada(through the Global Health Research Initiative),the Australian Agency for International Development for funding support,under funding number 105509-027 the International Joint Laboratory on Tropical Diseases Control in Greater Mekong Subregion from Shanghai Municipality Government(No.21410750200) 

主　　题：Schistosoma mekongi Opisthorchis viverrini Soil-transmitted helminth Parasite control Water Sanitation and hygiene Eco-Health/One-Health Lao PDR 

摘      要：Background Helminth infections,including Opisthorchis viverrini,hookworm,and Trichuris trichiura,are prevalent in Khong district,Champasack province,southern Lao People s Democratic Republic(PDR).Schistosomiasis caused by Schistosoma mekongi is of public health concern on the islands of the Khong *** study aimed to assess the impact of an Eco-Health/One-Health approach in combination with mass drug administration(MDA)to reduce these helminth *** We conducted a community intervention using a stepped-wedge trial approach on two endemic islands(Donsom and Donkhone)of the Khong district,Champasack province,Lao PDR,between April 2012 and March *** each study village,30-40 households were randomly *** members of selected households,who were at home during the study period were invited to participate in the study.A baseline study was conducted to assess helminth infections,knowledge attitudes and practices toward Schistosoma mekongi infection,behavior of open defecation and availability of latrine at *** the baseline(TO),the Eco-Health/One-Health approach was imple-mented on Donsom(intervention)and Donkhone island(control).An assessment was conducted in 2014(T1),one year after the completion of intervention implementation,to assess the short-term impact of the Eco-Health/One-Health approach on helminth infections and compare intervention and control *** in 2015,the Eco-Health/One-Health approach was implemented on control island(Donkhone).After the implementation of intervention,the parasitological assessments were conducted annually in humans in 2015(T2),in 2016(T3)and in 2017(T4),and in dogs in 2017(T4)to evaluate the long-term impact of the intervention on helminth *** was used to describe the prevalence of helminth *** regression was applied to associate the KAP(knowledge,attitudes,and practices and open defecation behavior)and the reduction of helminth infections between interventi