高温可能加重阻塞性睡眠呼吸暂停:一项基于智能手表监测的全国性分析（英文）

作     者：李安妮 张庆丽 姚远 诸心蕾 刘聪 郭玉涛 阚海东 陈仁杰 

作者机构：School of Public Health Key Lab of Public Health Safety of the Ministry of Education and NHC Key Lab of Health Technology Assessment Fudan University Ministry of Education-Shanghai Key Laboratory of Children's Environmental Health Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine Department of Pulmonary Vessel and Thrombotic Disease Sixth Medical Center Chinese PLA General Hospital Institute for Hospital Management Research Chinese PLA General Hospital Children's Hospital of Fudan UniversityNational Children's Medical Center School of Public Health Hengyang Medical School University of South China 

出 版 物：《Science Bulletin》 (科学通报(英文版))

年 卷 期：2024年第13期

页      面：2114-2121页

核心收录：

学科分类：1002[医学-临床医学] 08[工学] 080401[工学-精密仪器及机械] 0804[工学-仪器科学与技术] 100213[医学-耳鼻咽喉科学] 081102[工学-检测技术与自动化装置] 0811[工学-控制科学与工程] 10[医学] 

基　　金：supported by the Shanghai Municipal Science and Technology Major Project (2023SHZDZX02) Shanghai B&R Joint Laboratory Project (22230750300) Shanghai International Science and Technology Partnership Project (21230780200) the Shanghai Committee of Science and Technology (21TQ015) the Shanghai 3-year Public Health Action Plan (GWVI-11.2-YQ32) 

摘      要：Obstructive sleep apnea（OSA） is a serious type of sleep disorder that can lead to cardiometabolic and neurocognitive diseases. We utilized smart device-based photoplethysmography technology to collect sleep data from the Chinese population from 2019 to 2022. Distributed lag nonlinear models combined with a generalized nonlinear model or a linear mixed effects model were used to investigate the shortterm associations between daily temperature and indicators of OSA severity. We included a total of6,232,056 d of sleep monitoring data from 51,842 participants with moderate to severe risk of OSA from313 Chinese cities. The relationships between ambient temperature and OSA exacerbation, apneahypopnea index（AHI）, and minimum oxygen saturation（MinSpO2） were almost linear and present only on the same day. Higher temperatures were associated with a greater risk of OSA exacerbation, with an8.4%(95% confidence interval（CI）: 7.6%–9.3%) increase per 10 °C increase in temperature. A 10 °C increase in daily temperature corresponded to an AHI increase of 0.70 events/h（95% CI: 0.65–0.76）and a MinSpO2decrease of 0.18%（95% CI: 0.16%–0.19%）. Exposure to elevated temperatures during the night can also lead to adverse effects. The effects of higher temperatures on OSA severity were stronger among men, participants with a body mass index ≥ 24 kg/m2, those aged 45 years and older, individuals with a history of hypertension and diabetes, and during the cold season. This large-scale,nationwide, longitudinal study provides robust evidence suggesting that higher ambient temperatures may immediately worsen OSA.