Hospitalized prevalence and 5-year mortality for IBD:Record linkage study

作     者：Lori A Button Stephen E Roberts Michael J Goldacre Ashley Akbari Sarah E Rodgers John G Williams 

作者机构：School of MedicineSwansea UniversitySwansea SA2 8PPUnited Kingdom Unit of Health-Care EpidemiologyUniversity of OxfordOxford OX2 7LFUnited Kingdom 

出 版 物：《World Journal of Gastroenterology》 (世界胃肠病学杂志（英文版）)

年 卷 期：2010年第16卷第4期

页      面：431-438页

核心收录：

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

基　　金：Supported by The Health Foundation 

主　　题：Crohn’s disease Ulcerative colitis Prevalence Mortality Record linkage 

摘      要：AIM:To establish the hospitalized prevalence of severe Crohn s disease(CD) and ulcerative colitis(UC) in Wales from 1999 to 2007;and to investigate long-term mortality after hospitalization and associations with social deprivation and other socio-demographic ***:Record linkage of administrative inpatient and mortality data for 1467 and 1482 people hospitalised as emergencies for ≥ 3d for CD and UC,*** main outcome measures were hospitalized prevalence,mortality rates and standardized mortality ratios for up to 5 years follow-up after ***:Hospitalized prevalence was 50.1 per 100 000 population for CD and 50.6 for *** hospitalized prevalence of CD was significantly higher(P 0.05) in females(57.4) than in males(42.2),and was highest in people aged 16-29 years,but the prevalence of UC was similar in males(51.0) and females(50.1),and increased continuously with *** hospital-ized prevalence of CD was slightly higher in the most deprived areas,but there was no association between social deprivation and hospitalized prevalence of *** was 6.8% and 14.6% after 1 and 5 years follow-up for CD,and 9.2% and 20.8% after 1 and 5 years for *** both CD and UC,there was little discernible association between mortality and social deprivation,distance from hospital,urban/rural residence and ***:CD and UC have distinct demographic *** higher prevalence of hospitalized CD in more deprived areas may reflect higher prevalence and higher hospital dependency.