复发-缓解型多发性硬化症患者进行性灰质损害的证据
Evidence for progressive gray matter loss in patients with relapsing-remitting MS作者机构:Department of Neurology Scientific Institute University H San Raffaele Via Olgettina 60 20132 Milan Italy.Dr
出 版 物:《世界核心医学期刊文摘(神经病学分册)》 (Digest of the World Core Medical Journals.Clinical Neurology)
年 卷 期:2006年第2期
页 面:50-50页
学科分类:1002[医学-临床医学] 100204[医学-神经病学] 10[医学]
摘 要:Little is known about the temporal evolution of gray matter damage occurring early in the course of multiple sclerosis (MS). The authors investigated the evolution of gray matter volume loss in 117 patients with relapsing-remitting MS, scanned monthly for a 9-month period. Time-trend analysis revealed a decrease of gray matter volumes over the study period (p 0.001). This study shows that gray matter damage in relapsing-remitting MS evolves markedly over a short period of observation.