Clinical efficacy of laparoscopic cholecystectomy plus cholangioscopy for the treatment of cholecystolithiasis combined with choledocholithiasis

作     者：Chao-Hui Liu Zhi-Wei Chen Zhe Yu Hong-Yu Liu Jian-Sheng Pan Shuang-Shuang Qiu 

作者机构：Department of General SurgeryThe Affiliated Haixia Hospital of Huaqiao University(910th Hospital of Joint Logistic Support Force)Quanzhou 362000Fujian ProvinceChina Department of General SurgeryAnxi Hospital of Traditional Chinese MedicineQuanzhou 362499Fujian ProvinceChina 

出 版 物：《World Journal of Gastrointestinal Surgery》 (世界胃肠外科杂志（英文版）（电子版）)

年 卷 期：2024年第16卷第7期

页      面：2080-2087页

核心收录：

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

主　　题：Laparoscopic common bile duct exploration Endoscopic retrograde cholangiopancreatography Laparoscopic cholecystectomy Cholecystolithiasis Choledocholithiasis Clinical efficacy 

摘      要：BACKGROUND Currently,endoscopic retrograde cholangiopancreatography(ERCP)plus laparoscopic cholecystectomy(LC)is the main treatment for cholecystolithiasis combined with ***,the treatment is unsatisfactory,and the development of better therapies is *** To determine the clinical efficacy of LC plus cholangioscopy for cholecystolithiasis combined with *** Patients(n=243)with cholecystolithiasis and choledocholithiasis admitted to The Affiliated Haixia Hospital of Huaqiao University(910th Hospital of Joint Logistic Support Force)between January 2019 and December 2023 were included in the study;111 patients(control group)underwent ERCP+LC and 132 patients(observation group)underwent LC+laparoscopic common bile duct exploration(LCBDE).Surgical success rates,residual stone rates,complications(pancreatitis,hyperamylasemia,biliary tract infection,and bile leakage),surgical indicators[intraoperative blood loss(IBL)and operation time(OT)],recovery indices(postoperative exhaust/defecation time and hospital stay),and serum inflammatory markers[C-reactive protein(CRP)],tumor necrosis factor-α(TNF-α),and interleukin-6(IL-6)were *** No significant differences in surgical success rates and residual stone rates were detected between the observation and control ***,the complication rate,IBL,OT,postoperative exhaust/defecation time,and hospital stays were significantly reduced in the observation group compared with the control ***,CRP,TNF-α,and IL-6 Levels after treatment were reduced in the observation group compared with the levels in the control *** These results indicate that LC+LCBDE is safer than ERCP+LC for the treatment of cholecystolithiasis combined with *** surgical risks and postoperative complications were lower in the observation group compared with the control ***,patients may recover quickly with less inflammation after LCBDE.