A study on the effectiveness of intravenous tramadol in the management of severe traumatic pain in emergency department

作     者：Rashidi Ahmad Mohd Ghazali Abd Rashid Nasir Mohamad Kamarul Aryffin Baharuddin Mohd Ismail Ibrahim Rashidi Ahmad;Mohd Ghazali Abd Rashid;Nasir Mohamad;Kamarul Aryffin Baharuddin;Mohd Ismail Ibrahim

作者机构：Department of Emergency Medicine Department of Community MedicineSchool of Medical SciencesHealth campus of University Sains Malaysia 

出 版 物：《海南医学院学报》 (Journal of Hainan Medical University)

年 卷 期：2010年第16卷第7期

页      面：838-841,846页

学科分类：1003[医学-口腔医学] 1011[医学-护理学（可授医学、理学学位）] 100302[医学-口腔临床医学] 10[医学] 

主　　题：静脉注射 患者 软组织 曲马多 

摘      要：Introduction:Patients with pain contribute to 60%-70% of emergency department(ED)attendance and the tramadol is among analgesic of choice in ***,the use of intravenous tramadol is limited to moderate pain intensity because of its weak opiod agonist *** conducted a study to examine the effectiveness of intravenous tramadol among patients who suffer from severe traumatic ***:In this prospective study,eligible patients received a loading dose of intravenous tramadol(2mg/kg).If visual analogue score(VAS)more than 30 mm after the loading dose,intermittent bolus intravenous tramadol 20mg will be administered every 10 *** 30 minutes of study,rescue medication(*** or pethidine)will be provided to those patients with VAS more than 30 *** score,vital signs and side effects were recorded for every 10 minutesResults:Forty-seven patients who suffered from fracture and soft tissue injury were *** median VAS score on presentation and at 30 minutes was 90 mm 20 mm *** median total dose of IV tramadol received by the patients at 30 minutes was 150 mg(IQR=34.0).There was a significant change in medium pain score at 10,20 and 30 minutes treatment(P0.001).Vital signs were within normal range throughout the study *** 66.1% of them had side effects of *** common side effects were sleepiness(75.0%)and dizziness(56.3%).Conclusion:The intravenous tramadol is a safe and effective analgesia in severe traumatic patients if an initial and intermittent dose is given adequately.