1-Heptanesulfonic acid sodium salt:One pot efficient synthesis of 2-aryl-1-arylmethyl-1H-1,3-benzo[d]imidazoles
1-Heptanesulfonic acid sodium salt:One pot efficient synthesis of 2-aryl-1-arylmethyl-1H-1,3-benzo[d]imidazoles作者机构:Department of ChemistryDr.Babasaheb Ambedkar Marathwada UniversityAurangabadMaharashtra431004India Division of Medicinal ChemistryWockhardt Research CentreD-4Chikalthana M.I.D.C.AreaAurangabadMaharashtra431210India
出 版 物:《Chinese Chemical Letters》 (中国化学快报(英文版))
年 卷 期:2009年第20卷第5期
页 面:535-538页
核心收录:
学科分类:081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学]
主 题:1-Heptanesulfonic acid sodium salt Water Aryl aldehyde Benzimidazole
摘 要:Synthesis of 2-aryl-1-arylmethyl-1H-1,3-benzo[d]imidazoles by the reaction of o-phenylenediamine with substituted aromatic aldehydes in the presence of 1-heptanesulfonic acid sodium salt (10 mol%) at room temperature. The reactions were performed in acetonitrile:water (8:2). The method was proved to be eco-friendly, convenient and the products were isolated with good yields (82- 90%).