A rare presentation of unicentric Castleman's disease in the thigh:A case report and review of literature

作     者：Sultan AlSheikh Abdulmajeed Altoijry Husain Al-Mubarak Ofays Dakkam Alsallum Fadi Alakeel Tariq Alanezi 

作者机构：Division of Vascular SurgeryDepartment of SurgeryCollege of MedicineKing Saud UniversityRiyadh 11322Saudi Arabia Division of Vascular SurgeryDepartment of SurgeryKing Khalid Hospital NajranNajran 11321Saudi Arabia Department of PathologyCollege of MedicineKing Saud UniversityRiyadh 11322Saudi Arabia 

出 版 物：《World Journal of Clinical Cases》 (世界临床病例杂志)

年 卷 期：2024年第12卷第19期

页      面：4003-4009页

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

主　　题：Castleman’s disease Lymph nodes Surgical resection Lymphoproliferative disorder Case report 

摘      要：BACKGROUND Castleman s disease(CD)is a rare lymphoproliferative,emulating both benign and malignant *** diagnosis of CD is formulated upon the combination of clinical and laboratory criteria and ultimately confirmed by histopathological *** to its rarity,CD presents a challenge in treatment selection,with available options encompassing surgery,chemotherapy,and autologous stem cell ***,studies suggest that surgical resection of the lesion is the most effective treatment modality,especially for unicentric CD(UCD).CASE SUMMARY Here,we describe the case of a 25-year-old woman who presented with painless left thigh swelling for 10 *** had been following a low-fat diet to lose weight and had normal laboratory *** resonance imaging revealed a wellcircumscribed,demarcated cystic lesion located in the left inguinal region with eccentrically positioned signal void vascular structures,measuring 4.3 cm×3 cm×3.2 cm,likely of lymphoid *** patient underwent surgical resection,and the final histopathology showed a vascular proliferation and hyalinization of the vessel walls,along with atretic germinal centers traversed by penetrating vessels,consistent with *** patient was discharged home one day after the procedure in good condition,with a follow-up appointment scheduled in our outpatient *** Although surgical resection is the mainstay for UCD,a multidisciplinary approach is needed due the lack of specific diagnostic features and treatments.