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Atypical Guillain-Barrésyndrome with positive anti-sulfatide,anti-GT1b,and anti-GT1a antibodies:A case report

作     者:Fei-Fei Tan He-Xu Liu Xue-Yan Huang Chang-Yin Yu Xiao-Yan Yang 

作者机构:Department of NeurologyAffiliated Hospital of Zunyi Medical UniversityZunyi 563000Guizhou ProvinceChina 

出 版 物:《World Journal of Clinical Cases》 (世界临床病例杂志)

年 卷 期:2024年第12卷第20期

页      面:4372-4376页

学科分类:1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基  金:The Scientific and Technological Innovation Talent Team Project of Zunyi City,No.2 Guizhou Maotai Hospital Research and Talent Cultivation Funding Project,No.MTYK 2022-06 

主  题:Guillain-Barré Anti-sulfatide antibody Anti-GT1b antibody Anti-GT1a antibody Case report 

摘      要:BACKGROUND The role of diverse antibodies in mediating peripheral nerve injury in Guillain-Barrésyndrome(GBS)is becoming clearer,but positivity for multiple antibodies in one case is *** our knowledge,this is the first case involving GBS with positive anti-sulfatide,anti-GT1a,and anti-GT1b *** SUMMARY A 20-year-old female patient was admitted to the hospital due to weakness of limbs for 5 d,and deterioration of the weakness and muscle aches for 1 *** patient s limbs were weak,but the tendon reflexes in the part of the limbs were *** was no comorbid peripheral nociception or deep sensory *** was diagnosed with GBS and was discharged after receiving intravenous human immunoglobulin pulse *** In this article,the clinical manifestations,neurophysiological examination,and auxiliary examination findings of a GBS patient positive for multiple antibodies were analyzed to improve the identification of the disease by clinical physicians at an early stage.

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