GROWTH AND MORPHOLOGY OF POLYMER-ACTIN COMPLEXES

作     者：Hyuck Joon Kwon Kazuhiro Shikinaka Akira Kakugo Hidemitsu Furukawa Yoshihito Osada 龚剑萍 

作者机构：Graduate School of ScienceHokkaido UniversitySapporo 060-0810Japan Graduate School of ScienceHokkaido UniversitySapporo 060-0810Japan SORSTJSTSapporo 060-0810Japan 

出 版 物：《Chinese Journal of Polymer Science》 (高分子科学（英文版）)

年 卷 期：2007年第25卷第1期

页      面：47-55页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070305[理学-高分子化学与物理] 080501[工学-材料物理与化学] 0805[工学-材料科学与工程（可授工学、理学学位）] 0703[理学-化学] 

基　　金：This research is financially supported by SORST  JST and the Ministry of Education  Science  Sports  and Culture  Japan (Grant-in-Aid of Creative Scientific Research) 

主　　题：F-actin Polymer-actin complex Polycation concentration (Cp) KCl concentration (Cs) Fluorescence microscopy Transmission electron microscopy (TEM) Rod-like polyelectrolyte. 

摘      要：F-actins are semi-flexible polyelectrolytes and can be assembled into large polymer-actin complex with polymorphism through electrostatic interaction with polycations. This study investigates the structural phase behavior and the growth of polymer-actin complexes in terms of its longitudinal and lateral sizes. Our results show that formation of polymer-actin complexes is cooperative, and morphology and growth of polymer-actin complexes depend on polycation species and concentrations of polycation and salt in a constant actin concentration. We found that the longitudinal growth and lateral growth of polymer-actin complexes are dominated by different factors. This induces the structural polymorphism of polymer-actin complexes. Major factors to influence the polymorphism of polymer-actin complexes in polyelectrolytc system have been discussed. Our results indicate that the semi-flexible polyelectrolyte nature of F-actins is important for controlling the morphology and growth ofactin architectures in cell.