From non-alcoholic fatty liver disease to metabolic-associated steatotic liver disease:Rationale and implications for the new terminology

作     者：Stephen David Howard Malnick Doron Zamir 

作者机构：Department of Internal Medicine CKaplan Medical CenterRehovot 76100Israel Department of Internal Medicine DBarzilai Medical CenterAshkelon 7830604Israel 

出 版 物：《World Journal of Hepatology》 (世界肝病学杂志（英文版）（电子版）)

年 卷 期：2024年第16卷第6期

页      面：863-866页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Non-alcoholic fatty liver disease Steatosis metabolic-associated steatotic liver disease Nomenclature 

摘      要：Non-alcoholic fatty liver disease(NAFLD)was the term first used to describe hepatic steatosis in patients with the metabolic syndrome who did not consume excess amounts of *** liver disease(ALD)has many similarities to NAFLD in both pathogenesis and *** entity is now the most prevalent chronic liver disease worldwide as a consequence of the epidemic of *** to incorporate the importance of the metabolic syndrome in the development of steatosis resulted in the renaming of NAFLD as metabolic-associated fatty liver *** new term,however,has the disadvantage of the use of terms that may be perceived as *** terms fatty and non-alcoholic have negative connotations in many *** addition,non-alcoholic is not usually a term applicable to pediatric cases of hepatic ***,an international collaborative effort,with participants from 56 countries,after a global consultation process,recommended to change the nomenclature to steatotic liver disease-including metabolic dysfunction-associated steatotic liver disease,metabolic-associated steatohepatitis and metabolic dysfunction-associated *** new terminology is consistent with most of the previously published epidemiological studies and will have a major impact on research into diagnosis,prognosis and treatment.