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A Rare Case of Aortic Valve Endocarditis and Acute Meningitis Due to Haemophilus influenzae

A Rare Case of Aortic Valve Endocarditis and Acute Meningitis Due to Haemophilus influenzae

作     者:Zachary M. Visinoni Justin D. Tse Christopher F. Pease Zachary M. Visinoni;Justin D. Tse;Christopher F. Pease

作者机构:Department of Graduate Medical Education Internal Medicine Residency Sutter Roseville Medical Center Roseville USA Sutter Medical Group Roseville USA 

出 版 物:《Case Reports in Clinical Medicine》 (临床医学病理报告(英文))

年 卷 期:2024年第13卷第6期

页      面:207-211页

学科分类:1004[医学-公共卫生与预防医学(可授医学、理学学位)] 100401[医学-流行病与卫生统计学] 10[医学] 

主  题:HACEK Haemophilus influenzae Aortic Valve Endocarditis Bacterial Meningitis Cerebral Empyema 

摘      要:HACEK organisms represent a rare but important group of causative pathogens in endocarditis. These bacteria have historically been associated with culture-negative endocarditis;however, modern laboratory techniques have made this less common. In this case, we present a 74-year-old man who presented with acute onset altered mentation, fever, and sepsis. He was ultimately found to have Haemophilus influenzae meningitis, cerebral empyema, aortic valve endocarditis, psoas myositis, and L2 - L3 diskitis with osteomyelitis. Although HACEK organisms are commonly found in the oropharynx and upper respiratory tract in humans, our patient did not report recent preceding dental or ENT procedures. H. influenzae is responsible for approximately 0.16% of all cases of bacterial endocarditis, representing a very limited subset. Although generally considered low virulent pathogens, this case demonstrates the unusual extent of infection from a HACEK organism, H. influenzae, causing aortic valve endocarditis as well as atypical non-cardiac sequelae, including acute meningitis.

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