Mechanism of modified Chaihu Shugan formula in the treatment of epilepsy based on IncRNA-UCA1/miR-187/MAPK8 pathway

作     者：李瑞暖 LI Ruinuan

作者机构：Guangxi Molec Biol Key LabTCM Prev&TreatGraduate SchGuangxi TCM UnivNanning 530023 

出 版 物：《China Medical Abstracts(Internal Medicine)》 (中国医学文摘（内科学分册（英文版）)

年 卷 期：2024年第41卷第1期

页      面：13-14页

学科分类：1008[医学-中药学(可授医学、理学学位)] 1006[医学-中西医结合] 100602[医学-中西医结合临床] 10[医学] 

主　　题：epilepsy Chaihu UCA1 

摘      要：Objective To observe the effects of Modified Chaihu Shugan Formula (MCSF) on the behavior of epileptic mice and their regulatory effects on long noncoding RNAUCA1(lncRNA-UCA1),microRNA-187(miR-187) and recombinant mitogen activated protein kinase 8(MAPK8).Methods Totally 80 mice were randomly divided into normal group,model group (pilocarpine hydrochloride 180 mg/kg).