Assessment of post-myocardial infarction lipid levels and management:Results from a tertiary care hospital of Pakistan
作者机构:Department of Preventive CardiologyNational Institute of Cardiovascular DiseasesKarachi 75510Pakistan Department of Adult CardiologyNational Institute of Cardiovascular DiseasesKarachi 75510Pakistan Department of CardiologyLiaquat National HospitalKarachi 74800Pakistan
出 版 物:《World Journal of Cardiology》 (世界心脏病学杂志(英文版)(电子版))
年 卷 期:2024年第16卷第5期
页 面:282-292页
学科分类:1002[医学-临床医学] 100201[医学-内科学(含:心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学]
基 金:NICVD
主 题:Lipid profile Dyslipidemia Acute myocardial infarction Secondary prevention Lipid lowering therapy
摘 要:BACKGROUND Lipid treatment practices and levels in post-acute myocardial infarction(AMI)patients,which are crucial for secondary *** To evaluate the lipid treatment practices and lipid levels in post-myocardial infarction(MI)patients at a tertiary care hospital in *** In this cross-sectional study,we analyzed patients who had experienced their first AMI event in the past 3 *** assessed fasting and non-fasting lipid profiles,reviewed statin therapy prescriptions,and examined patient *** recommended dose was defined as rosuvastatin≥20 mg or atorvastatin≥40 mg,with target total cholesterol levels set at160 mg/dL and target low-density lipoprotein cholesterol(LDL-C)at55 mg/*** Among 195 patients,71.3%were male,and the mean age was 57.1±10.2 *** median duration since AMI was 36(interquartile range:10-48)months and 60% were diagnosed with ST-segment elevation *** 13.8% of patients were advised to undergo lipid profile testing after AMI,88.7% of patients were on the recommended statin therapy,and 91.8% of patients were compliant with statin *** 11.5% had LDL-C within the target range and 71.7% had total cholesterol within the target *** admission in the past 12 months was reported by 14.4%,and the readmission rate was significantly higher among non-compliant patients(37.5%vs 5.6%).Subsequent AMI event rate was also significantly higher among non-compliant patients(43.8%vs 11.7%).CONCLUSION Our study highlights that while most post-AMI patients received the recommended minimum statin therapy dose,the inadequate practice of lipid assessment may compromise therapy optimization and raise the risk of subsequent events.