Fecal microbiota transplantation in the treatment of hepatic encephalopathy:A perspective
作者机构：Department of Pediatric GastroenterologySanjay Gandhi Postgraduate Institute of Medical SciencesLucknow 226014India
出 版 物：《World Journal of Hepatology》 (世界肝病学杂志（英文版）（电子版）)
年 卷 期：2024年第16卷第5期
页 面：678-683页
学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学]
主 题：Fecal microbiota Dysbiosis Hepatic encephalopathy Cirrhosis
摘 要：Due to its complex pathogenesis,treatment of hepatic encephalopathy(HE)continues to be a therapeutic *** late,gut microbiome has garnered much attention for its role in the pathogenesis of various gastrointestinal and liver diseases and its potential therapeutic *** evidence suggests that gut micro-biota plays a significant role in cerebral *** in the gut microbiota has been documented in patients with HE in a number of clinical and experimental *** on gut dysbiosis in patients with HE has opened newer therapeutic avenues in the form of probiotics,prebiotics and the latest fecal microbiota transplantation(FMT).Recent studies have shown that FMT is safe and could be effective in improving outcomes in advanced liver disease patients presenting with ***,questions over the appropriate dose,duration and route of administration for best treatment outcome remains unsettled.
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