Controlled semi-Pinacol rearrangement on a strained ring:Efficient access to multi-substituted cyclopropanes by group migration strategy

作     者：Wenyu Gao Liming Zhang Chuang Zhao Lixiang Liu Xingran Yang Jinbo Zhao 

作者机构：Faulty of Chemistry and Life ScienceChangchun University of TechnologyChangchun 130012China 

出 版 物：《Chinese Chemical Letters》 (中国化学快报（英文版）)

年 卷 期：2024年第35卷第9期

页      面：135-139页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：Financial support of this work from National Natural Science Foundation of China(No.21871045) startup funding from Changchun University of Technology 

主　　题：Cyclopropeneα-carbinols Electrophile addition Semi-Pinacol rearrangement Cyclopropane 

摘      要：We describe a versatile electrophile addition/SPR sequence of readily available cyclopropyl carbinols that affords multi-substituted carbonylated cyclopropanes with high *** approach tolerates various heteroatom electrophiles,migration of carbon moiety of all possible hybridization states,facile ring reorganization and natural compound *** examples represent an unprecedented version of SPR wherein migration to a non-benzylic bulky tertiary carbo-cation is realized with promising enantiocontrol.