Has Coca-Cola treatment become the first-line therapy for gastric bezoars,both in general and specifically for western countries?

作     者：Maria Delgado Galan Luis Ramon Rabago 

作者机构：Department of GastroenterologyHospital Severo OchoaLeganes 28914Spain Department of GastroenterologyHospital San RafaelMadrid 28016Spain 

出 版 物：《World Journal of Gastrointestinal Endoscopy》 (世界胃肠内镜杂志（英文版）（电子版）)

年 卷 期：2024年第16卷第5期

页      面：237-243页

学科分类：1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 10[医学] 

主　　题：Phytobezoars Endoscopic treatment Oral dissolution treatment with Coca-Cola Randomized study Editorial 

摘      要：Phytobezoars is a rare disease and less common in Western *** stomach is the primary site for these formations,and endoscopic treatment involving fragmentation and extraction has traditionally been the most effective ***,medical treatments using enzymatic and chemical agents,such as cellulase and Coca-Cola,aimed at dissolving the bezoars,have also been utilized,showing varying degrees of resolution ***,the oral dissolution treatment with Coca-Cola has emerged as a promising,simpler,and more costeffective *** study by Liu et al represents an important step in clinical research on this topic,despite some limitations that need addressing for a more comprehensive understanding of its *** considerations for future research include sample size calculation,endoscopic procedure details,outpatient *** treatment,and detailed cost *** study s exclusions,such as patients with upper gastric surgery,phytobezoars older than 14 d,and cases of gastroparesis,limit its applicability to broader populations,especially in Western *** the promising outcomes of the Coca-Cola treatment,it s advocated as a first-line therapy for ***,further research is essential to overcome these *** special situations such as perforation or small bowel obstruction will require surgical treatment.