Prognostic factors associated with gastrointestinal dysfunction after gastrointestinal tumor surgery:A meta-analysis

作     者：Jia Song Cong Zhou Tian Zhang 

作者机构：Department of Operating RoomThe Fourth Affiliated Hospital of Nanjing Medical UniversityNanjing 210031Jiangsu ProvinceChina Department of Gastrointestinal SurgeryTongji Hospital of Huazhong University of Science and TechnologyWuhan 430073Hubei ProvinceChina Department of Disinfection Supply CenterThe Fourth Affiliated Hospital of Nanjing Medical UniversityNanjing 210031Jiangsu ProvinceChina 

出 版 物：《World Journal of Gastrointestinal Surgery》 (世界胃肠外科杂志（英文版）（电子版）)

年 卷 期：2024年第16卷第5期

页      面：1420-1429页

核心收录：

学科分类：100218[医学-急诊医学] 1002[医学-临床医学] 1010[医学-医学技术（可授医学、理学学位）] 100214[医学-肿瘤学] 10[医学] 

主　　题：Gastrointestinal tumor surgery Postoperative gastrointestinal dysfunction Intestinal paralysis Risk factors Metaanalysis 

摘      要：BACKGROUND Explore the risk factors of gastrointestinal dysfunction after gastrointestinal tumor surgery and to provide evidence for the prevention and intervention of gastrointestinal dysfunction in patients with gastrointestinal tumor *** To investigate the potential risk factors for gastrointestinal dysfunction following gastrointestinal tumor surgery and to present information supporting the prevention and management of gastrointestinal dysfunction in surgery *** Systematically searched the relevant literature from PubMed,Web of Science,Cochrane Library,Embase,CNKI,China Biomedical Database,Wanfang Database,and Weipu Chinese Journal Database self-established until October 1,*** Manager 5.3 software was used for meta-analysis after two researchers independently screened literature,extracted data,and evaluated the risk of bias in the included *** A total of 23 pieces of literature were included,the quality of which was medium or above,and the total sample size was *** results of meta-analysis showed that the patients were male(OR=1.58,95%CI:1.25-2.01,P=0.002)and≥60 years old(OR=2.60,95%CI:1.76-2.87,P0.001),physical index≥25.3 kg/m2(OR=1.6,95%CI:1.00-1.12,P=0.040),smoking history(OR=1.89,95%CI:1.31-2.73,P0.001),chronic obstructive pulmonary disease(OR=1.49,95%CI:1.22-1.83,P0.001),enterostomy(OR=1.47,95%CI:1.26-1.70,P0.001),history of abdominal surgery(OR=2.90,95%CI:1.67-5.03,P0.001),surgical site(OR=1.2,95%CI:1.40-2.62,P0.001),operation method(OR=1.68,95%CI:1.08-2.62,P=0.020),operation duration(OR=2.65,95%CI:1.92-3.67,P0.001),abdominal adhesion grade(OR=2.52,95%CI:1.90-3.56,P0.001),postoperative opioid history(OR=5.35,95%CI:3.29-8.71,P0.001),tumor TNM staging(OR=2.58,95%CI:1.84-3.62,P0.001),postoperative blood transfusion(OR=2.92,95%CI:0.88-9.73,P=0.010)is a risk factor for postoperative gastrointestinal dysfunction in patients with gastrointestinal *** There are many factors affecting gastroint