“Bad regenerators” die after spinal cord injury:insights from lampreys

作     者：Antón Barreiro-Iglesias 

作者机构：Department of PhysiologyDevelopment and NeuroscienceUniversity of Cambridge 

出 版 物：《Neural Regeneration Research》 (中国神经再生研究（英文版）)

年 卷 期：2015年第10卷第1期

页      面：25-27页

核心收录：

学科分类：1002[医学-临床医学] 100210[医学-外科学(含：普外、骨外、泌尿外、胸心外、神外、整形、烧伤、野战外)] 10[医学] 

主　　题：Bad regenerators die after spinal cord injury SCI 

摘      要：In mammalian species, including humans, spinal cord in- jury （SCI） leads to permanent disability. A major cause of disability after SCI is the failure of axotomized descending axons to regenerate across the trauma zone and to reconnect to they appropriate targets distal to the site of injury. Cur- renfly, major research efforts are devoted to find new ways of promoting the regrowth of damaged descending axons. However, activation of axonal regrowth will depend on the survival of the axotomized descending brain neurons.