Mechanisms of liver injuries caused by traditional Chinese medicines

作     者：Shui-Fang Jin Qi Pan Jin-Peng Zhou Xiao-Ping Pan Shui-Fang Jin;Qi Pan;Jin-Peng Zhou;Xiao-Ping Pan

作者机构：Intensive Care UnitThe First Affiliated Hospital of Zhejiang Chinese Medical University(Zhejiang Provincial Hospital of Chinese Medicine)Hangzhou 310006China Institute of Liver DiseasesCollege of Basic Medical SciencesZhejiang Chinese Medical UniversityHangzhou 310053China The Second Clinical Medical College of Zhejiang Chinese Medical UniversityHangzhou 310056China 

出 版 物：《Hepatobiliary & Pancreatic Diseases International》 (国际肝胆胰疾病杂志（英文版）)

年 卷 期：2024年第23卷第3期

页      面：310-312页

核心收录：

学科分类：1002[医学-临床医学] 10[医学] 

基　　金：This study was supported by grants from Zhejiang Health Science and Technology Project(2022ZA052) Zhejiang Provincial Natural Science Foundation of China(LY23H030001). 

主　　题：drugs tuberculosis TCM 

摘      要：Drug-induced liver injury(DILI)is a common adverse drug reaction,which can even result in liver failure[1,2].The Chinese Medical Association issued the Guidelines for the Diagnosis and Treatment of DILI based on the Roussel Uclaf Causality Assessment Method(RUCAM)in 2015[3].A previous study reported that traditional Chinese medicines(TCMs),herbal and dietary supplements,and antituberculosis drugs were the main causes of DILI in China[4].Herb-induced liver injury(HILI)refers to liver injury caused by TCMs,natural drugs,and their related preparations[5].