Synthesis,Crystal Structure and Antibacterial Activity of (2E,3E)-N^1,N^2-Bis(2,3,4-trimethoxy-6-methylbenzylidene)ethane-1,2-diamine

作     者：李建 梁足培 孔凡亭 张慧 台西市 

作者机构：Department of Chemistry and Chemical Engineering Weifang UniversityWeifang 261061 China Jinan Chemical Fertilizer Plant Co. Ltd.Jinan 250101 China 

出 版 物：《Chinese Journal of Structural Chemistry》 (结构化学（英文）)

年 卷 期：2009年第28卷第5期

页      面：577-579页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：supported by the Natural Science Foundation of Shandong Province (No. Y2007B61) 

主　　题：synthesis crystal structure antibacterial activity 

摘      要：The title compound （2E,3E）-N1,N2-bis（2,3,4-trimethoxy-6-methylbenzylidene）- ethane-l,2-diamine （C24H32N2O6, Mr = 444.52） was synthesized and characterized by elemental analysis, IR spectra and single-crystal X-ray diffraction. The crystal belongs to triclinic, space group P2/c, with a = 8.5480（10）, b = 9.3710（12）, c = 15.280（2）A, β = 90.780（2）°, V= 1223.9（3）A3, Z = 2, Dc= 1.206 g/cm3, 2 = 0.71073A,μ（MoKa） = 0.087 mm^-1, F（000） = 476, the final R = 0.0680 and wR = 0.1450 for 2144 observed reflections with I 〉 2σ（I）. X-ray diffraction analysis reveals that the molecule adopts an E configuration about the central C=N functional bond. The phenyl rings of two 2,3,4-trimethoxy-6-methylbenzaldehyde groups are symmetrically parallel. The molecules are linked through C-H…O hydrogen bonding interactions. The title compound possesses moderate antibacterial activity.