Recent advances on vaccines against malaria: A review

作     者：Shiza Malik Yasir Waheed Shiza Malik;Yasir Waheed

作者机构：Bridging Health FoundationRawalpindi 46000Pakistan Gilbert and Rose-Marie Chagoury School of MedicineLebanese American UniversityByblos 1401Lebanon MEU Research UnitMiddle East UniversityAmman11831Jordan 

出 版 物：《Asian Pacific Journal of Tropical Medicine》 (亚太热带医药杂志（英文版）)

年 卷 期：2024年第17卷第4期

页      面：143-159页

核心收录：

学科分类：1004[医学-公共卫生与预防医学(可授医学、理学学位)] 1002[医学-临床医学] 100201[医学-内科学(含：心血管病、血液病、呼吸系病、消化系病、内分泌与代谢病、肾病、风湿病、传染病)] 100401[医学-流行病与卫生统计学] 10[医学] 

主　　题：Vaccines against malaria Drugs and adjuvant Malarial treatment Plasmodium RTS,S vaccine 

摘      要：This review aims to summarize the currently viable vaccine strategies including the approved vaccines and the those in trials for next-generation malaria *** on malaria vaccine development was collected through a comprehensive *** literature search was performed using databases including Google Scholar,PubMed,NIH,and Web of *** novel approaches of vaccination are being developed,including those based on radiation-attenuated strategies,monoclonal antibodies,targeted immunogenic peptides,RNA and DNA vaccines,nanoparticle-based vaccines,protein-based vaccination protocols,and whole organism-based vaccination *** on RTS,S have entered phase Ⅲtesting,and those based on blood-stage vaccines and vaccines to interrupt malarial transmission have advanced to higher stages of *** modeling,combined drug and vaccine strategies,mass drug administration,polyvalent vaccine formulations,and targeted vaccination campaigns is playing an important role in malarial ***,assessing coverage,accessibility,acceptability,deployment,compilation,and adherence to specific vaccination strategies in endemic regions is essential for vaccination drives against malaria.