Decarboxylative Amination with Nitroarenes via Synergistic Catalysis

作     者：Meiling Ding Sitian Zhou Shunruo Yao Chengjian Zhu Weipeng Li Jin Xie Meiling Ding;Sitian Zhou;Shunruo Yao;Chengjian Zhu;Weipeng Li;Jin Xie

作者机构：State Key Laboratory of Coordination ChemistryJiangsu Key Laboratory of Advanced Organic MaterialsChemistry and Biomedicine Innovation Center(ChemBIC)School of Chemistry and Chemical EngineeringNanjing UniversityNanjingJiangsu210023 China Green Catalysis Centerand College of ChemistryZhengzhou UniversityZhengzhouHenan450001 China 

出 版 物：《Chinese Journal of Chemistry》 (中国化学（英文版）)

年 卷 期：2024年第42卷第4期

页      面：351-355页

核心收录：

学科分类：07[理学] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：National Key Research and Development Program of China(2022YFA1503200,2021YFC2101901) the National Natural Science Foundation of China(22122103,22101130,22001117,21971108,22271144) Fundamental Research Funds for the Central Universities(020514380304,020514380252,020514380272)for financial support. 

主　　题：Nitroarenes Amines Synergistic catalysis Carboxylic acids Radical alkylation Amination Photocatalysis Steric hindrance 

摘      要：In this paper,we have developed a decarboxylative amination of carboxylic acids with nitroarenes for the synthesis of secondary amines.The protocol is performed at mild conditions without the use of noble metals as catalysts.A wide range of structurally diverse secondary amines could be obtained in good yields(up to 94%)with good functional group tolerance.This transformation shows good to excellent selectivity,avoiding the generation of over alkylated byproducts.