Unveiling the culprit:the fusobacterium lineage that populates colorectal cancer

作     者：Johannes Betge Matthias P.Ebert Johannes Betge;Matthias P.Ebert

作者机构：Department of Medicine ⅡMedical Faculty MannheimHeidelberg UniversityMannheimGermany Junior Clinical Cooperation Unit Translational Gastrointestinal Oncology and Preclinical ModelsGerman Cancer Research Center(DKFZ)HeidelbergGermany DKFZ Hector Cancer Institute at University Medical CenterMannheimGermany MMPU Microbiota Drug Metabolism and Cancer TherapyEuropean Molecular Biology LaboratoryHeidelbergGermany 

出 版 物：《Signal Transduction and Targeted Therapy》 (信号转导与靶向治疗（英文）)

年 卷 期：2024年第9卷第6期

页      面：2349-2350页

核心收录：

学科分类：1002[医学-临床医学] 100214[医学-肿瘤学] 10[医学] 

基　　金：supported by the Hector Ⅱ Foundation 

主　　题：colorectal al. cancer 

摘      要：In a recent study published in Nature,Zepeda-Rivera et al.1 discovered that one distinct clade of Fusobacterium nucleatum animalis(Fna)dominates the colorectal cancer(CRC)tumor *** work unravels a more precise understanding of a major bacterial species associated with CRC progression,thereby establishing a new focus for future studies,which may aid to develop improved microbiome-based diagnostics and treatments(Fig.1).