Rhodium-Catalyzed Regioselective C-O and C-C Bonds Formation of 3-Oxopent-4-enenitriles with Alkynes for the Synthesis of Polysubstituted 2H-Pyrans

作     者：Kelu Yan Xiao Liu Jiangwei Wen Qiuyun Li Junjie Wang Yang Zheng Xiu Wang 

作者机构：Key Laboratory of Life-Organic Analysis of Shandong ProvinceSchool of Chemistry and Chemical EngineeringQufu Normal UniversityQufuShandong273165China Faculty of Chemistry and Chemical EngineeringYancheng Institute of TechnologyYanchengJiangsu 224051China 

出 版 物：《Chinese Journal of Chemistry》 (中国化学（英文版）)

年 卷 期：2024年第42卷第17期

页      面：1986-1992页

核心收录：

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：National Natural Science Foundation of China, NSFC, (22101152) National Natural Science Foundation of China, NSFC Youth Talent Program Startup Foundation of Qufu Normal University, (614201) Yancheng Institute of Technology, YCIT, (xjr2020044) Yancheng Institute of Technology, YCIT 

主　　题：Rhodium/C-H activation 3-Oxopent-4-enenitriles Alkynes 2H-Pyrans Transition metals Regioselectivity Cyclization Comprehensive Summary 

摘      要：The rhodium-catalyzed C-H bond activation and cyclization of 3-oxopent-4-enenitriles with alkynes proceed *** 2H-pyrans with multiple substituents are achieved in good yields through regioselective formation of C-O and C-C *** involving hydroxy-alkynoates resulted in products with a furo[3,4-b]pyran skeleton via further intramolecular ester exchange *** from the traditional1-oxatrienes pathway,this method for the synthesis of useful 2H-pyrans possesses certain highlights in terms of readily available substrates,stable and easily derivatized products,gentle and convenient operation process,and step and atomeconomy.