A Bronchopulmonary Onset of Candidemia Revealing a Granulomatosis with Polyangiitis
A Bronchopulmonary Onset of Candidemia Revealing a Granulomatosis with Polyangiitis作者机构：Department of Internal Medicine Ibn Rochd University Hospital Center Casablanca Morocco
出 版 物：《Case Reports in Clinical Medicine》 (临床医学病理报告（英文）)
年 卷 期：2024年第13卷第5期
页 面：147-154页
学科分类：1007[医学-药学(可授医学、理学学位)] 10[医学]
主 题：Candidemia C. glabrata Pulmonary Candidiasis Vasculitis Immunodepression Granulomatosis with Polyangiitis Cavitary Lesions Antifungal Therapy Immunosuppressants
摘 要：Candidemia is defined as being a yeast infection confirmed by the presence of at least one positive Candida blood culture. It is a life threatening infection causing high mortality. The clinical signs are generally compatible with the causative agent (whether there is a deep venous catheter or not). On the other hand and according to the 2012 Revised Chapel Hill Classification, granulomatosis with polyangiitis GPA is classified as a vasculitis associated with antineutrophil cytoplasmic antibodies ANCA. It is a systemic disease characterized by the anatomopathological aspect of granuloma. We report the case of a patient who presented an atypical and a very rare revealing mode of GPA which was a bronchopulmonary candidiasis complicated by candidemia. Despite its controversy, the combination in the acute phase of antifungal treatment based on intravenous voriconazole and glucocorticoid therapy has made it possible to control candidemia and calm vasculitis.
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