Matrix Metalloproteinase-9 in the Etiopathogenesis of Placenta Accreta Spectrum:A Literature Review

作     者：Putri Mirani Peby Maulina Lestari Krisna Murti Iche Andriyani Liberty Hana Andrina Cindy Kesty Bella Stevanny 

作者机构：Division of Maternal-Fetal MedicineDepartment of Obstetrics and GynecologyDr.Mohammad Hoesin General Hospital/Faculty of Medicine Sriwijaya UniversityPalembangSouth SumateraIndonesia Division of Hematolymphoid and EndocrinologyDepartment of Pathological AnatomyDr.Mohammad Hoesin General Hospital/Faculty of Medicine Sriwijaya UniversityPalembangIndonesia Department of Public Health and Community MedicineFaculty of MedicineSriwijaya UniversityPalembangIndonesia Department of Obstetrics and GynecologyDr.Mohammad Hoesin General Hospital/Faculty of Medicine Sriwijaya UniversityPalembangSouth SumateraIndonesia. 

出 版 物：《Maternal-Fetal Medicine》 (母胎医学杂志（英文）)

年 卷 期：2024年第6卷第2期

页      面：97-101页

核心收录：

学科分类：1002[医学-临床医学] 100211[医学-妇产科学] 10[医学] 

主　　题：Biomarker Etiopathogenesis Matrix metalloproteinase MMP-9 Placenta accreta spectrum disorder 

摘      要：The recent increase in placenta accreta spectrum has been correlated with a rise in the rate of cesarean sections.A recent study provides evidence that hampered wound healing results in cesarean scar defects that lead to a failure in the normal process of decidualization and deeper adherence of *** metalloproteinase(MMP)is crucial in every step of wound healing as it alters the wound matrix,facilitating cell migration,as well as tissue ***-9 expression is higher in placental and decidual tissue in cases of placenta *** on these findings,assessment of MMP-9 expression can shed new light on the etiopathology of placenta accreta spectrum disorder and can be a potential diagnostic marker.